Using the example of changing jobs: At the very least, changing your job means a new routine for you and the people around you. In more extreme cases a new job can mean moving home, sacrificing a partner's career or having to study for new qualifications.
Whether the changes are large or small it is difficult to avoid the fact that career decision making affects more than just work.
Approached in the right way, complex issues can be changed from dilemmas into opportunities for progress. Admittedly, the solutions aren't any easier but the ability to interpret situations and make informed decisions can be considerably improved.